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In the Danube River Basin, five main pressures that affect water status: organic substance pollution, nutrient pollution, hazardous substance pollution, hydromorphological alterations and effects of climate change (drought, water scarcity, extreme hydrological phenomena and other impacts), have been identified as Significant Water Management Issues (SWMIs). The groundwater quantity and quality are also under constant pressure.

Despite the EU's advanced waste management and ambitious recycling objectives, studies still indicate the presence of macro and microplastic pollution in EU rivers. The Tid(y)Up project focuses on improving water quality and reducing plastic pollution in the Tisza River, which is long considered one of Europe’s most heavily contaminated rivers.

Rivers, lakes, transitional and coastal waters, as well as groundwater, are vital natural resources. A significant proportion of water resources are exposed to environmental pollution or other potentially damaging pressures. Protecting and improving the waters of the Danube River Basin is therefore essential for the natural environment, the sustainable development of the region and the long-term health, well-being, and prosperity of the population.

A recent large-scale modelling study has shown that restoring floodplains and reconnecting cut-off water bodies with the Danube River, and its tributaries could play a significant role in improving water quality and removing nitrate pollution in the Danube River Basin.