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The Joint Danube Survey 2001 was carried out by the ICPDR and is the most homogenous analysis of the water quality and the ecological status of the Danube River. Over 140 chemical and biological parameters were analysed and over 40.000 laboratory results were generated.

The TransNational Monitoring Network is an important tool under the Danube River Protection Convention (DRPC), whose Contracting Parties are committed to co-operate in the field of monitoring and assessment. Formally launched in 1996, the TNMN aims to provide a well-balanced overall view of pollution and long-term trends in water quality and pollution loads in the major rivers in the Danube River Basin.

daNUbs was a mulitnational EU research project carried out under the leadership of the Technical University of Vienna. The results from this project include estimates of nutrient inputs into the river network (MONERIS), as well as an assessment of the loads of nitrogen, phosphorus and silica transported via the river network. These results indicate that the nutrient status in the Black Sea has significantly improved since the 1980s.

Organic pollution has been on the rise in the Danube over the last century, as human activities have resulted in increasing loads of wastewater rich in organic matter. The most serious organic pollution problems occur in tributaries that regularly receive untreated or inadequately treated wastewater from industrial plants and municipalities. Thanks to the significant improvement of wastewater infrastructure and services in the Danube countries, the basin-wide organic emissions reduced by 60% since the mid 2000s.