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The International Commission for the Protection of the Danube River (ICPDR) works to ensure the sustainable and equitable use of waters in the Danube River Basin. The work of the ICPDR is based on the Danube River Protection Convention (DRPC), the major legal instrument for cooperation and transboundary water management in the Danube River Basin.

The Danube River Basin is Europe's second largest river basin, with a total area of 801,463 km². It is the world's most international river basin, flowing through the territory of 19 countries. The ecosystems of the Danube River Basin are highly valuable in environmental, economic, historical and social terms, but they are subject to increasing pressure and serious threats of pollution from agriculture, industry and cities.