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North Macedonia, officially the Republic of North Macedonia, is a landlocked country in Southeast Europe. Its terrain is mostly rugged, located between the Šar Mountains and Osogovo, which frame the valley of the Vardar River. Three large lakes - Lake Ohrid, Lake Prespa, and Dojran Lake - lie on the southern borders, bisected by the frontiers with Albania and Greece. Ohrid is considered one of the world's oldest lakes and biotopes.

The Monitoring and Assessment (MA EG) deals with ICPDR activities concerning surveillance as well as investigative monitoring and water quality analyses.

Water quality in the Danube has improved over the years, but there is still much work to be done to meet the region’s goals for water status. To improve the water quality, an ambitious programme of measures for the whole Danube River Basin District has been agreed under the EU WFD. To assess trends in water quality, the ICPDR oversees the TransNational Monitoring Network (TNMN). The network carefully monitors physical, chemical and biological conditions in the Danube and its tributaries, and provides in TNMN Yearbooks an annual overview of pollution levels as well as long term trends for water quality in the basin.