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Following a request by the Danube Ministerial Conference 2010, the ICPDR has become active in initiating a dialogue with representatives from the hydropower sector. As an essential step in this process, "Guiding Principles on Sustainable Hydropower Development in the Danube Basin" have been developed by an interdisciplinary team and were finalised and adopted in June 2013.

Hazardous substances can remain in the environment for a very long time, and harm ecosystems and human health. Although monitoring indicates that the loads of some substances have been reduced in recent years, many problems still persist. The increasing number of these man-made substances present in the environment is a matter of concern, and calls for the application of the precautionary principle.